Bubonic plague (black death) is a specific infectious disease, usually appearing in epidemic form, of extraordinary virulence and very rapid course with a tendancy to linger and recur once it has attacked a community. It is characterised by inflammation of the lymphatic glands, by parenchymatous changes in the cerebal membranes, the lungs, kidneys, and other organs, by carbuncles, and often by haemorrhages. It is caused by the organism Bacillus pestis. In 1665 the bubonic plague killed over 70,000 inhabitants in London. Research Bubonic Plague