Carpal tunnel syndrome is a common disorder that causes pain, and interferes with the use of the hand. It is caused by pressure on the mediannerve as the nerve passes through a canal formed by the bones and ligaments in the wrist (the carpal tunnel). A wide variety of conditions can cause the carpal tunnel to narrow and put pressure on the mediannerve, including injuries, such as wrist fractures; arthritis complicated by swelling of the tendons in the carpal tunnel; pregnancy, which may cause the synovium around the tendons to thicken; and glandular abnormalities, such as diabetes and thyroid disorders. Work that involves repetitive wrist motions may also cause carpal tunnel syndrome. Symptoms of carpal tunnel syndrome include pain and numbness in the thumb and in the index, middle, and ring fingers. Many people wake at night with these symptoms. Some sufferers experience weakness of hand muscles and may drop objects. Symptoms often occur when the wrist is flexed during such activities as driving a car or holding a book while reading.
Doctors treat carpal tunnel syndrome by attempting to improve the underlying condition. In many cases, doctors apply a splint to the wrist and prescribe anti-inflammatory medications. In some cases, surgery is performed to relieve symptoms and to prevent permanent damage to the mediannerve. Research Carpal tunnel syndrome
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