The Probert Encyclopaedia of Medicine

FIBRINOGEN

Fibrinogen is one of the three main components of plasma. The other two being globulins and albumin. Only 3% of plasma is made up of fibrinogen. It is an important link in the chain of reactions that leads to blood clotting. It uses the enzyme thrombin to form a web of fine protein fibres, called fibrin, that bind blood cells together, creating a bridge over which injured tissue can rebuild itself while blood continues to flow underneath. As an important factor to coagulation, it is often referred to as factor I.
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