The opponens digiti minimi (opponens digiti quinti) lies immediately beneath the flexor digiti minimi brevis. It is triangular in shape and originates from the hamulus of the hamate bone and the flexor retinaculum of the wrist. It inserts in the fifth metacarpal bone. The opponens digiti minimi is innervated by the ulnar nerve and supplied by the ulnar artery. This muscle is a part of the hypothenar eminence, the muscle mass of the little finger, located on the outside of the palm of the hand. The hypothenar eminence consists of the abductor digiti minimi, the flexor digiti minimi brevis, the opponens digiti minimi, and the palmaris brevis. These muscles work together to perform the grasp functions of the hand. With the help of the opponens digiti minimi, the little finger can be brought across to touch the thumb. Research Opponens Digiti Minimi