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The Probert Encyclopaedia of Medicine

PHYSOTIGMINE

Physotigmine is an alkaloid derived from the Calabar Bean. It has little effect on the cerebrum, but acts strongly on the vital centres in the medulla, and on the spinal cord where it produces feebleness of muscular movement, and slightly affects sensation. It was used in medicine where it was given to relieve tetanus and to antagonise the action of atropine and to relieve ocular tension.
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