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The Probert Encyclopaedia of Medicine

SYPHILIS

Syphilis is a venereal disease (VD, STD) due to the micro-organism Treponema Pallidum. It is usually transmitted by sexual contact with an infected person, but may also be transmitted by contact with an infected person through cuts or scratches in the skin, making medical staff particularly at risk of contracting the disease. The initial stage of syphilis is a 'chancre' which resembles a large infected wart. It appears on the lips or in the genital area, but frequently this stage of the disease is overlooked and heals spontaneously.

Primary syphilis, as this stage is called, may then pass unnoticed. The secondary stage lasts for several weeks and is characterised by rashes and ulcerative lesions in the mouth. This stage also may be overlooked and if treatment is not instituted the patient will develop tertiary syphilis of which there are various manifestations. One is the development of a syphilitic tumour or gumma which breaks down and produces an ulcer - gummatous ulcer. Tertiary syphilis also affects the nervous system, producing tabes dorsalis (locomotor ataxia). In this condition the victim develops degenerative changes in the joints (Charcot's joints) and perforating ulcers in the feet. The child of an infected mother may be born with congenital syphilis which shows itself during the first two or three years of life in special changes which affect the child's bones, liver and eyes.
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