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The Probert Encyclopaedia of Medicine

VIOXX

Vioxx is a trade name for Rofecoxib, a Cox-2 inhibitor, potentially deadly anti-inflammatory drug manufactured by the American drug company Merck and Company during the early 1990s and widely hailed as a 'wonder drug'. Upon investigation it was found that the side effects of using the drug were frequently heart-attacks or strokes. Doctors and academics who sought to investigate the possible dangers of Vioxx were harassed and threatened by the company manufacturing Vioxx, who also strongly lobbied the American government to promote its prescription and use as a pain relief for arthritis. In February 2005 the American FDA, presumably under pressure and advice from the various manufacturers of cox-2 inhibitors, voted to continue approval of cox-2 inhibitors including Vioxx despite its potentially deadly side-effects.
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