Anne (known as Brandy Nan after her fondness for brandy) was Queen of Great Britain and Ireland from 1702 to 1714. She was born in 1664 at Twickenham and died in 1714. She was the second daughter of James II, then Duke of York and his wife Anne, daughter of the Earl of Clarendon. With her father's permission she was educated according to the principles of the English Church. In 1683 she was married to Prince George, brother to King Christian V. of Denmark. On the arrival of the Prince of Orange in 1688, Anne wished to remain with her father; but she was prevailed upon by LordChurchill (afterwards Duke of Marlborough) and his wife to join the triumphant party. She ascended the throne in 1702 following the death of William III. Her character was essentially weak, and she was governed first by Marlborough and his wife, and afterwards by Mrs. Masham. Most of the principal events of her reign are connected with the war of the Spanish Succession. The only important acquisition that England made by it was Gibraltar, which was captured in 1704. Another very important event of this reign was the union of England and Scotland under the name of Great Britain, which was accomplished in 1707. She seems to have long cherished the wish of securing the succession to her brother James, but this was frustrated by the internal dissensions of the cabinet. Grieved at the disappointment of her secret wishes, she fell into a state of weakness and lethargy, and died, on July the 20th, 1714. The reign of Anne was distinguished not only by the brilliant successes of the British arms, but also on account of the number of admirable and excellent writers who flourished at this time, among whom were Pope, Swift, and Addison. Anne bore her husband many children, all of whom died in infancy except one son, the Duke of Gloucester, who died at the age of twelve. Research Anne
Encephalitis Lethargica or sleepy sickness is a disease of comparatively late recognition. It has been known in Europe, America and Great Britain since about 1916. The virus is unknown, but the disease is characteristic, causing fever, lethargy and paralysis of the eyemuscles with double vision. Infection probably takes place through the mouth and nose. Various non-typical forms of the disease also occur. The onset is often gradual and insidious, but sometimes acute delirium may be the first symptom. The condition often resembles influenza in the early stages, and hiccough is a common symptom. In severe cases mania or delirium is seen, or lethargy and coma; muscular pains, rigidity of the limbs, or convulsions may develop. Later, in cases which recover, tremors and purposeless movements may indicate the true condition and the patient's face becomes mask-like and expressionless ('Parkinsonism'). A drooping posture and the shuffling gait are characteristic, The diagnosis is often difficult; about 33 per cent. of cases are fatal. Complete
recovery is rare, most cases ending in chronic invalidism, and the disease often runs on for many months. There is no specific treatment. Isolation and careful nursing are essential. Hyoscine, Artane and Benadryl relieve tremors, and stiffness ollimbs. Research Encephalitis Lethargica
Myalgic encephalomyelitis (ME or 'yuppy flu') is a poorly defined collection of symptoms characterized by aching muscles, depression and lethargy which often follow a virus infection, particularly glandular fever. The name is misleading, since encephalitis means an inflamation of the brain and spinal cord, which are not present in the condition. It has been suggested that 'post viral fatigue syndrome' would be a more appropriate name for the condition. Research Myalgic Encephalomyelitis
Myxoedema (Hypothyroidism) is a disease caused by a lack of thyroid hormones, sometimes due to the destruction of thyroid or pituitary tissue. A deficiency of thyroid hormones causes a depression of cellular enzyme systems, manifesting itself in lethargy, a reduction in body temperature, intolerance to the cold, reduced attention span, memory loss, fatigue and muscle weakness. Research Myxoedema
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Matt and Leela Probert
Abbreviations
Research Anne
