The Ziesel reaction is a method of determining the number of methoxy (-OCH3) groups in an organiccompound. The compound is heated with excess hydriodic acid, forming an alcohol and iodomethane. The iodomethane is distilled off and led into an alcoholic solution of silvernitrate, where it precipitates silver iodide. This is filtered and weighed, and the number of iodine atoms and hence methoxy groups can be calculated. The method was developed by S. Ziesel in 1886. Research Ziesel Reaction
 
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